抗酒石酸酸性磷酸酶（TRAP，tartrate-resistant acid phosphatase）为破骨细胞的标志酶，特异地分布于破骨细胞中，为破骨细胞所特有。通常作为鉴别破骨细胞的重要标志物，使破骨细胞呈红色。Kamiya艾美捷抗酒石酸酸性磷酸酶TRAP染色试剂盒，经众多Nature文章使用认证！

Kamiya艾美捷抗酒石酸酸性磷酸酶TRAP染色试剂盒应用：

① 破骨细胞TRAP染色

② 破骨细胞培养上清液中TRAP活性的测定

Kamiya艾美捷抗酒石酸酸性磷酸酶TRAP染色试剂盒Nature文章结果鉴赏：

①【Nature Medicine, IF=87.2】  

TRAP stain: TRAP染色 (osteoclasts (o/c))

图1

② 【Nature Biomedical Engineering, IF=29.2】A multi-organ chip with matured tissue niches linked by vascular flow  

TRAP Activity: TRAP活性

图2

更多发表文章： 

Kim, Jinkoo, et al. "Erythropoietin mediated bone formation is regulated by mTOR signaling."Journal of cellular biochemistry113.(2012): 220-228.

Lee, Yu-Chen, et al. "Src family kinase/abl inhibitor dasatinib suppresses proliferation and enhances differentiation of osteoblasts."Oncogene 29.22 (2010): 3196-3207.

Lu, Yi et al. "Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone". Clinical & experimental metastasis vol.26,2 (2009): 161-9. doi:10.1007/s10585-008-9226-7